Universal Application of Modern Tissue Engineering in Oral and Maxillofacial Reconstruction

Abstract: With the advancements made in regenerative medicine, the predictability and reliability of tissue-engineered bone grafts have made the reconstruction of defects in the oral and maxillofacial region a reassuring and dependable process, eliminating the need for harvesting autogenous bone. Long-term clinical studies have demonstrated that this mixture is equivalent to or superior to avascular autogenous bone graft.

The presentation will comprehensively cover the preoperative workup, preparation, and procedural options for patients with congenital defects, benign tumors, post-resection defects, and traumas. In addition, the speaker will provide a thorough review of initial evaluation, patient selection, and state-of-the-art science regarding growth factors and autogenous bone substitutes. Emphasis will be placed on surgical technique, postoperative care, and management of complications, ensuring that the audience is well-informed and prepared.

Topics for mandibular regeneration will be covered, ranging from socket preservation and alveolar ridge defects to continuity defects, and even the reconstruction and regeneration of the condyle. Also, “controversies” of modern bone grafting will be addressed.

The session will focus on the use of cutting-edge contemporary tissue engineering (Stem cells, allogeneic bone, and BMP-2) to reconstruct the maxillofacial region, ensuring the most effective and successful outcomes for our patients and instilling optimism about the future of maxillofacial reconstruction.

Learning Objectives:
1). Describe the current clinical application of tissue engineering for maxillofacial defects.
2). Identify challenges faced by the clinical reconstruction maxillofacial defects.
3). Compare and contrast several management strategies for patients mandibular and maxillary defects.