Clinical review of bone regenerative medicine and maxillomandibular reconstruction

We have studied bone regenerative medicine to employ autologous bone marrow stromal cells and platelet-rich plasma as tissue-engineered osteogenic materials. Although our studies have been successful to a certain degree, advancing to clinical applications, the strategy for practical use of this method has to be changed, because the environment surrounding bone regenerative medicine has evolved dramatically.

Therefore, we have changed our focus from cells to cell-conditioned media, and we found that the latter contains growth factors and matrices released from the cells and promotes regeneration of tissues by recruiting endogenous stem cells and precursor cells, and thereby started clinical research based on these findings.

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Osteo Science Foundation
1650 Market Street, Suite 3600
Philadelphia, PA 19103
215-977-2877
855-891-2877 Toll Free
info@osteoscience.org

Osteo Science Foundation is an independent, privately funded 501 (c) (3) non-profit organization.

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