Matrix-associated chondrocyte transplantation

Matrix-associated chondrocyte transplantation for reconstruction of articulating surfaces in the temporomandibular joint: a pilot study covering medium- and long-term outcomes of 6 patients

One important aim of the field of tissue engineering (TE) is to replace degenerated tissues with cells and scaffolds that restore tissue function and mediate regeneration. 

During the past decades, matrix-associated chondrocyte transplantation (MACT) has emerged as a disease-modifying treatment with excellent clinical longterm results in patients with isolated cartilage injuries and osteochondral lesions in the knee joint.1

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