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Congratulations to Mark E. K. Wong, DDS, FACD, FACS on receiving the Robert V. Walker Distinguished Service Award

Written on September 22, 2022

Osteo Science Foundation Board Chair, Mark E. K. Wong, DDS, FACD, FACS, received the Robert V. Walker Distinguished Service Award on Wednesday, September 14, 2022, at the 104th AAOMS Annual Meeting Opening Ceremony. This award recognizes significant contributions to the specialty of Oral and Maxillofacial surgery and is the highest accolade presented by the AAOMS.

Osteo Science Foundation’s First OMS Research Fellow

Written on March 24, 2022

We are thrilled to announce our first OMS Research Fellow, Sarah Wong PhD. Learn more about Dr. Wong and the program!

Congratulations To The 103rd AAOMS Annual Meeting Resident Travel Award Recipients

Written on August 24, 2021

Congratulations To The 103rd AAOMS Annual Meeting Resident Travel Award Recipients

Mark Wong, DDS, Board Chair

Mark Wong, DDS, Board Chair

Written on August 24, 2021

Osteo Science Foundation is thrilled to announce Mark E.K. Wong, DDS, as the Chair of Osteo Science Foundation Board of Directors.

R. Gilbert Triplett, DDS, PhD ft. in AAOMS Today

Written on July 31, 2020

Thank you to R. Gilbert Triplett, DDS, PhD Chair of Osteo Science Foundations’s Clinical and Scientific Review Committee 2014-2020

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David Roe, DMD, a resident at Montefiore Medical C

David Roe, DMD, a resident at Montefiore Medical Center, participated in the Clinical Observership Program in December 2021. Dr. Roe visited David Urbanek, DMD at Midwest Oral Maxillofacial & Dental Surgery in St. Louis, MO for a two week experience in a private practice setting.

Exploration Tuesday is here! Have you read this ar

Exploration Tuesday is here! Have you read this article? Take a few minutes to read our summary on this regenerative medicine article.

Three-dimensional printing technologies enable the fabrication of patient-matched implants for craniofacial bone reconstruction and tissue regeneration. In the case of tissue regeneration, scaffolds with complex internal geometries can be realized with 3D printing that might not be possible with traditional manufacturing techniques. However, the overall success of the approach requires material properties amenable to the 3D printing process and compliant with the requirements to support bone regeneration. A recent study by Manzoor et al. investigated various composites of polyetheretherketone (PEEK) and hydroxyapatite (HA)-based particles for potential scaffold fabrication via a fused deposition modeling format of 3D printing. The investigators reported that inclusion of HA particles (alone, doped with strontium, or doped with zinc) increased the bioactivity of the PEEK material, as reflected in mineralization over the course of 28 days of immersion in simulated body fluid in vitro. While the inclusion of the HA-based particles (10 wt%) was found to increase the viscosity of the polymer composite and increase the melting temperature, the investigators were successful in forming filaments with each composite that were compatible with the fused deposition modeling process. Inclusion of HA particles in the composites resulted in a slight decrease in the ultimate tensile strength and Young’s modulus of 3D-printed samples, but the authors suggest that tensile mechanical properties were suitable for craniofacial bone tissue engineering applications. Overall, the study underscores the importance of appropriately balancing material properties for fabrication via 3D printing of patient-matched scaffolds for craniofacial bone repair.

Want more article summaries? Visit https://www.osteoscience.org

Register for our in person meeting, "Regenerative

Register for our in person meeting, "Regenerative Solutions to Common Problems," February 18-19, in Austin, TX. Get $100 OFF General Admission when you use the code INSTAGRAM at checkout. For more details and to register go to https://www.osteoscience.org
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*Only 1 promo code may be used per registration. Promo codes only valid when applied to the general ticket pricing.

We are pleased to offer (5) $1,000 travel awards t

We are pleased to offer (5) $1,000 travel awards to OMS residents and dental students to attend the 2022 AADOCR/CADR Annual Meeting & Exhibition. This meeting will take place in Atlanta, Georgia on March 21-26.

Applicants must have an accepted abstract for AADOCR (whether they are presenting a poster or oral presentation), and it must be in the field of regenerative medicine.

The application is open now through February 14. Apply at https://www.osteoscience.org/research-grant-programs/our-grant-programs/resident-travel-awards/

Today is the final day to submit an application fo

Today is the final day to submit an application for the Osteo Science OMS Research Fellowship. Go to https://www.osteoscience.org/omsfellowship/ now to apply.

#omfsmatch #omsmatch #omsmatchday #matchday #omsre

#omfsmatch #omsmatch #omsmatchday #matchday #omsresident

You won’t want to miss this lineup! Check out th

You won’t want to miss this lineup! Check out the schedule of events with featured speakers & presentations for our upcoming meeting, “Regenerative Solutions To Common Problems.” Register at www.osteoscience.org

Our Scientific and Education Liaison, Myron Tucker

Our Scientific and Education Liaison, Myron Tucker, DDS, went to the University of Nebraska Medical Center to lecture to their oral surgery group in person and the orthodontic program in Lincoln virtually. Dr. Tucker then went to University of Oklahoma and lectured to the oral maxillofacial surgeons and combined orthodontic group.

He also got to spend some time with Dr. Robert Lamb, who was a dental school classmate of his 45 years ago. Dr. Lamb is now on the faculty at University of Oklahoma OMS.

“An amazing trip and wonderful experience.” -Myron Tucker, DDS

Designed especially for individuals in between den

Designed especially for individuals in between dental school and OMS residency, the Osteo Science Foundation OMS Research Fellowship is a unique career development opportunity offering hands-on research experience in regenerative medicine with a strong one-on-one mentoring component.

Based at one of our participating sites, Fellows will get a career jump-start through this one-year, intensive lab-based training program focused on regenerative medicine research.

The application submission cycle closes on January 31. Apply at https://www.osteoscience.org/advances

Join us on this fine Exploration Tuesday! Take a c

Join us on this fine Exploration Tuesday! Take a closer look at an article that explores advances in regenerative medicine. Plus explore our website with a library of articles like this one.

Tissue engineering strategies involving transplantation of stem cells to promote craniofacial bone regeneration often employ mesoderm-derived cell populations, such as bone marrow-derived mesenchymal stem cells. However, much of the craniofacial skeleton derives from neural crest stem cells, and the potential effect of the embryonic origin of the cell population used in craniofacial bone regenerations strategies remains unresolved. A recent article by Srinivasan et al. directly compared the osteogenic potential of an ectomesenchymal stem cell population (eMSCs) derived from human embryonic stem cells through a neural crest intermediate with mesodermal-derived adult bone marrow mesenchymal stem cells (BM-MSCs) in vitro and in a rat calvarial defect model. Two-dimensional cell culture experiments found that cells from each population were capable of induced differentiation along osteogenic, chondrogenic, and adipogenic lineages, although the adipogenic potential of the eMSCs was lower than that of BM-MSCs. When cultured on three-dimensional poly(-caprolactone)-tricalcium phosphate (PCL-TCP) scaffolds, the eMSCs showed greater proliferation, comparable mineralization, and differential gene expression compared with the BM-MSCs. PCL-TCP scaffolds seeded with eMSCs or BM-MSCs each promoted bone formation over 8 weeks of implantation in bilateral 5-mm diameter rat calvarial defects, as measured via micro-computed tomography and histomorphometry. Overall, the study demonstrates comparable levels of in vitro and in vivo osteogenic potential of the eMSC and BM-MSC populations investigated, and it suggests that eMSCs may be a promising cell source for craniofacial bone tissue engineering.

We are pleased to introduce Jasjit Dillon, MBBS, D

We are pleased to introduce Jasjit Dillon, MBBS, DDS, FDSRCS, FACS, one of the speakers that will be lecturing at our upcoming meeting "Regenerative Solutions to Common Problems." Dr. Dillon will present “Medication-Related Osteonecrosis,” on February 19. Please read on for her abstract and learning objectives. To watch her presentation in person, visit https://ecs.page.link/FStUy to register to join us in Austin.

Abstract
You have been referred a 65 female on a bisphosphonate for an extraction and immediate dental implant on #19. What is the best way to proceed? The patient wants to know her risk of medication-related osteonecrosis of the jaws (MRONJ) and what you will do to reduce it? This comprehensive overview of MRONJ will cover this and more. It will review medications that cause MRONJ and which ones are more problematic, along with the frequency and risk of disease. It will review risk and prevention strategies. The staging and current management including the latest research, clinical trials, and future treatment therapies will also be reviewed.

Learning Objectives
1. Understand the etiology and risk of developing MRONJ
2. Understand the risk of MRONJ with different classes of drugs
3. Be aware of future preventative research in the management of MRONJ

Bach Le, DDS, MD will present at our February Meet

Bach Le, DDS, MD will present at our February Meeting, "Regenerative Solutions to Common Problems" on February 18 & 19. Please read the abstract and learning objectives for Dr. Le's presentation, "Bone Graft Complications," and go to https://www.osteoscience,org to register now.

Abstract
Failures and complications associated with bone augmentation can have a devastating effect on the outcome of dental implant treatment. These complications are classified as either early or late. Early complications include wound dehiscence, membrane and graft exposure, and infection, with the most common complication being wound dehiscence. Late complications of bone augmentation are now recognized more frequently and include late resorption, foreign body reaction, late breakdown of grafted sites, lack of keratinized tissue and poor esthetics, as well as implant failure. This clinical presentation will focus on how to identify and avoid potential complications before they arise and how to manage many of the common complications that can occur with bone augmentation procedures. Emphasis will be given to risk assessment, classifications of complications, and treatment of challenging failures.

Learning Objectives
1. Identify patient-related risk factors associated with bone augmentation procedures
2. Identify anatomical-related risk factors associated with bone augmentation procedures
3. Diagnose and treat complications related to bone augmentation surgery

Robert A. Levine DDS, FCPP, FISPPS will join us at

Robert A. Levine DDS, FCPP, FISPPS will join us at our meeting to present, "Soft Tissue Grafting and the Importance of Phenotype Conversion Around Dental Implants: A Periodontal Plastic Surgeon’s Perspective."

To register today visit https://www.osteoscience.org

Abstract
There is growing evidence of the importance of both soft and hard tissue dimensions around dental implants in the prevention of short-term and long- term complications. This presentation will focus on the benefits of “phenotype conversion” using autogenous tissue grafts as well as collagen matrices whose usage comes with less patient morbidity. Dr. Levine will also share his publications co-authored with Dr. Mauricio Araujo (University of Maringa, Brazil) on a series of single tooth immediate central incisor implants with CBCT and clinical analysis testing the “10 Keys” principles as it relates to long-term clinical and radiographic success.

Learning Objectives
1. Recognize and apply the benefits to your practice of the “10 Keys for Successful Esthetic-Zone Immediate Implants” as it relates to the diagnostic, surgical, and prosthetic phases
2. The importance of soft and hard tissue augmentation for usage in both esthetic and non-esthetic areas for long-term success from single tooth to full arch
3. Describe the indications and benefits for the use of a new volume-stable collagen matrix to augment soft tissue thickness around dental implants and its important role in “phenotype conversion”
4. To understand the recent documented evidence supporting the usage of “phenotype conversion” around dental implants including a series of clinical studies to be published by Dr. Levine and his clinical research group

Nicholas Makhoul, DMD, MD, an Osteo Science Founda

Nicholas Makhoul, DMD, MD, an Osteo Science Foundation Peter Geistlich Research Award Recipient, will present, "Microvascular Reconstruction of the Maxilla and Mandible," at our upcoming meeting, "Regenerative Solutions to Common Problems." Read on for the presentation abstract and learning objectives.

Abstract
Reconstruction of the maxillofacial region poses many challenges and continues to be one of the most difficult tasks of an Oral and Maxillofacial surgeon. In the past few decades, a focus on improving patient form and functionality has driven advancements in the field. With the advent of free microvascular tissue transfer, patients requiring large hard and soft tissue reconstruction have had improved results than what was acceptable in the past. In addition, our application of computer aided design and manufacturing has made predictable functional reconstruction even more attainable. Even with these recent advancements our pursuit for perfection has yet to be realized as we explore new methods to solve an age-old problem.

Learning Objectives
1. Review of principles for maxillofacial reconstruction
2. Free tissue reconstruction technique
3. Use of computer aided surgical design and 3D printing in reconstruction
4. Future directions in facial reconstruction

Robert E. Marx, DDS, FACS will join us at our meet

Robert E. Marx, DDS, FACS will join us at our meeting to present, "Practical Access to Stem Cells for Oral and Maxillofacial Surgery."

To register today visit https://www.osteoscience.org

Abstract
Today’s point of care in-situ tissue engineering can reconstruct large continuity defects of the mandible and cystic defects as well as regenerate sufficient bone to place dental implants with ridge augmentation procedures! The components of predictable in-situ tissue engineering have been shown to be cells, a signal, i.e., rhBMP-2/ACS, and a matrix, i.e., cancellous allogeneic bone +/or fibrin, fibronectin, vitronectin. As defects become larger and the tissue bed becomes more compromised with scar, radiation, or poor vascularity, a greater number of osteoprogenitor cells/stem cells is required. Three existing bone marrow harvesters have shown the ability to regenerate bone in jaws to varying degrees. Data on these three systems will be compared as well as outcomes in bone regeneration.

Learning Objectives
1. The attendee will learn where the largest number of stem cells and osteoprogenitor cells reside in the donor sites of the tibia, anterior ilium, and posterior ilium
2. The attendee will learn of appropriate markers for stem cells as well as the counts in CFU-f’s to look for to assess stem cell yield
3. The attendee will be able to assess and know the difference in bone marrow aspiration devices related to a straight needle versus a flexible needle, and the value of aspirate upon removal of the needle or going forward

We will also be joined by Michael K. McGuire, DDS

We will also be joined by Michael K. McGuire, DDS who will give his presentation on February 18! To learn more and register now visit https://www.osteoscience.org

Abstract
Our goal in soft tissue reconstruction is to maximize clinical outcomes while reducing morbidity. New devices are being introduced that may be able to achieve these goals. This program will explore autogenous tissue alternatives along with evidence-based decision trees on when alternatives should be considered and how to improve outcomes.

Learning Objectives
1. Upon completion of this presentation, participants should be able to:
2. Explain the objectives of soft tissue augmentation
3. Compare various techniques and how they differ from the gold standard • Discuss the advantages of alternative therapy

James C. Melville, DDS, FACS will present, "From B

James C. Melville, DDS, FACS will present, "From Bench to Bedside: The Evolution of Tissue Engineered Maxillofacial Reconstruction," with Dr. Simon Young.

Abstract
First conceptualized by W.T. Green in the 1970s, the advent of tissue engineering was a significant milestone in the field of medicine and surgery. What startedas proof-of-concept studies in preclinical models has transitioned to clinically applicable regenerative strategies for maxillofacial reconstruction in patients. Tissue-engineered bone grafts have made the reconstruction of defects of the oral and maxillofacial region predictable and reliable without the need for harvesting autogenous bone. The "bench" part of this session will introduce and discuss the science regarding bone and nerve repair and regeneration.
The "bedside" session will focus on key concepts for the successful clinical application of tissue engineering science to bone and nerve repair. This session will briefly discuss preoperative workup, preparation, and procedural options for patients with tumors, post-resection defects, and traumatic defects.

Learning Objectives
1. Discuss the fundamental science behind tissue-engineering with a focus on cutting-edge strategies for bone and nerve regeneration
2. Review clinical strategies for bone and nerve regeneration to optimize patient outcomes
3. Review surgical techniques and the management of complications

Register for the meeting now at https://www.osteoscience.org

Craig M. Misch, DDS, MDS, the Osteo Science Founda

Craig M. Misch, DDS, MDS, the Osteo Science Foundation Education Committee Chair, will present "Point/Counterpoint: Vertical Defects in the Esthetic Zone – Prosthetic or Surgical Solutions?" with Dr. Bach Le at our February Meeting, "Regenerative Solutions to Common Problems."

Abstract
Patients with missing teeth in the “esthetic zone” may present with severe hard and soft tissue loss. While many techniques offer excellent results for reconstruction of these defects, few can be said to guarantee success. A bone augmentation procedure to correct a vertical defect in the esthetic zone that is not fully successful in correcting the defect often ensures the use of prosthetic pink. This leads to the treatment dilemma: “If we have to use a little pink, why not use a lot of pink” and spare the patient the painful bone augmentation in the first place? The aim of this lecture is to critically evaluate the current evidence to determine the predictability of various bone augmentation techniques for vertical ridge defects for implant placement and when to consider more conservative alternative treatment options.

Learning Objectives
1. Discuss the methods for vertical bone augmentation in the anterior maxilla
2. Understand the limitations of augmentation and implant replacement of multiple missing teeth in the esthetic zone
3. Discuss surgical approaches to prepare the anterior maxilla for the prosthetic solution to defect management

Robert Sader, MD, DDS, PhD is a speaker at our upc

Robert Sader, MD, DDS, PhD is a speaker at our upcoming meeting "Regenerative Solutions to Common Problems." Dr. Sader will present, "Bone Augmentation and Reconstruction: Keystones to Stimulate the Regeneration Process," on February 19, 2022 at the Four Seasons Austin.

Abstract
Reconstruction of complex shaped vertical and lateral bony defects is still a challenging problem for the surgeon, and complications and failures in osseous regeneration constantly occur, especially when bone substitutes are used or blended or when the patient's tissues are medically compromised. On the base of the human bone physiology and its regenerative healing mechanisms the fundamental mechano-biological keystones in surgical bone augmentation and reconstruction are presented in a step-by-step approach. Considering the biological requirements in unpredictable stability, early loading and enhanced neo-vascularisation by application of autologous blood concentrates, the complication rate can be reduced and bone augmentation can be performed more successfully even in very compromised patients such as in irradiated bone with application of advanced techniques.

Learning Objectives
1. Understand the bone physiology regarding its regeneration processes and capacities
2. Assess the different available bone substitutes and surgical techniques
3. Avoid complications by strictly following physiologically based surgical augmentation principles

We will also be joined by Frank Schwarz, DMD who w

We will also be joined by Frank Schwarz, DMD who will give his presentation on day two of our meeting, "Regenerative Solutions to Common Problems."

Abstract
Previous studies have indicated that surgical treatment of peri-implantitis with concomitant placement of a bone filler is associated with clinical and radiographic improvements on both short- and long-term periods. However, the available evidence also suggests that the effectiveness of regenerative treatment approaches is influenced by several factors, such as the type and configuration of the defect and implant surface characteristics, as well as the method of surface decontamination.

Learning Objectives
1. Surgical techniques and materials for regenerative therapy of peri- implantitis associated defects
2. Various decontamination protocols
3. Combination procedures for advanced defects (resective/regenerative)
4. The indication for soft tissue volume grafting
5. Indication based flap and suturing techniques

You will not want to miss Simon Young, DDS, MD, Ph

You will not want to miss Simon Young, DDS, MD, PhD, FACS lecturing with Dr. James C. Melville to present, "From Bench to Bedside: The Evolution of Tissue Engineered
Maxillofacial Reconstruction".

Visit https://www.osteoscience.org to read the learning objectives and abstract for this presentation.

The countdown is on! There is one month left to re

The countdown is on! There is one month left to register for our upcoming meeting, "Regenerative Solutions to Common Problems."

Our room block is expiring on January 21. If you are planning on attending the meeting please consider booking a room at the Four Seasons Austin, which is the site of the meeting. Reservations must be made by calling the hotel directly at 512-685-8100. Please reference Osteo Science Foundation in order to receive the discounted rate of $319/night plus applicable occupancy and sales tax. Rates are subject to applicable sales and occupancy taxes, which are currently 15% but are subject to change. A $4.50 state-cost recovery fee will be added to each room. *Please note that you will not be extended the discounted rate if you book online.

Visit https://www.osteoscience.org/education/educational-events/meeting-austin-2022/ to register now.

We are thrilled to announce our most recent Peter

We are thrilled to announce our most recent Peter Geistlich Research Award Recipient, Luiz E. Bertassoni, DDS, PhD. Dr. Bertassoni's research project is titled "3D Printing of Nano-Mineralized and Pre-Vascularized Scaffolds for Vertical Bone Augmentation." To read more about Dr. Bertassoni, as well as his abstract, visit https://www.osteoscience.org

Don't forget to check out our recent webinar featuring Dr. Bertassoni, where he discusses the research conducted in his lab. Go to https://ecs.page.link/wd3Hu to watch.
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#OSF #OsteoScienceFoundation #MaxillofacialSurgery #CraniomaxillofacialSurgery # OralSurgeon #OralSurgeons #OralSurgery #RegenerativeMedicine #OMFS #OMS #Maxillofacial #Research #podcast #OralMaxillofacial #OMFSResident #Webinar

We are pleased to introduce Jasjit Dillon, MBBS, D

We are pleased to introduce Jasjit Dillon, MBBS, DDS, FDSRCS, FACS, one of the speakers that will be lecturing at our upcoming meeting "Regenerative Solutions to Common Problems." Dr. Dillon will present “Medication-Related Osteonecrosis,” on February 19. Please read on for her abstract and learning objectives. To watch her presentation in person, visit https://www.osteoscience.org to register to join us in Austin.

Abstract
You have been referred a 65 female on a bisphosphonate for an extraction and immediate dental implant on #19. What is the best way to proceed? The patient wants to know her risk of medication-related osteonecrosis of the jaws (MRONJ) and what you will do to reduce it? This comprehensive overview of MRONJ will cover this and more. It will review medications that cause MRONJ and which ones are more problematic, along with the frequency and risk of disease. It will review risk and prevention strategies. The staging and current management including the latest research, clinical trials, and future treatment therapies will also be reviewed.

Learning Objectives
1. Understand the etiology and risk of developing MRONJ
2. Understand the risk of MRONJ with different classes of drugs
3. Be aware of future preventative research in the management of MRONJ

Happy Exploration Tuesday! The success of tissue

Happy Exploration Tuesday!

The success of tissue engineering constructs in large craniofacial bone defects depends to a great degree upon successful vascularization after implantation. While some bone tissue engineering approaches seek to develop prevascularized constructs capable of anastomosis with host vasculature upon implantation, the cells applied in the development of the constructs should be readily available to enable clinical translation. A recent article by Roux et al. reports the application of co-cultures of endothelial cells derived from pluripotent stem cells (iPSC-ECs) and mesenchymal stem cells (MSCs) toward the development of vascular networks for bone tissue engineering. The team combined iPSC-ECs with MSCs at various ratios to form spheroids. The spheroids were encapsulated in fibrin hydrogel scaffolds, and vascular network development was assessed via immunofluorescent staining for CD31 after three weeks of culture. A statistical design of experiments technique was applied to predict outcomes associated with various experimental parameters (e.g., cell ratio and fibrin concentration), and an optimal prevascularized unit formulation was determined. The investigators combined the optimized prevascularized units with hydroxyapatite nanoparticles to form composite hydrogel constructs, which they applied for bone regeneration in a rat calvarial defect model. The cellular content of constructs in one group comprised both iPSC-ECs and MSCs, while the constructs in the other group contained MSCs only. The iPSC-EC/MSC prevascularized constructs presented significantly higher blood vessel density than MSC-only constructs after 8 weeks of implantation, as quantified microscopically. The iPSC-EC/MSC-derived networks persisted throughout 8 weeks of implantation, and perfusion of lectin at that time point suggested that the network anastomosed with surrounding host vasculature. Overall, the study suggests the potential for endothelial cells derived from iPSCs to form prevascularized constructs for craniofacial bone tissue engineering that integrate with host vasculature.

To read the full article visit https://www.osteoscience.org/advances

Join us for a two-day event in Austin, Texas to he

Join us for a two-day event in Austin, Texas to hear experts in regenerative medicine discuss Regenerative Solutions to Common Problems. Each day we will showcase one of our speakers along with their presentation title and abstract. For more information on our upcoming meeting visit https://osteoscience.org

New year new advances in regenerative medicine art

New year new advances in regenerative medicine article summary! "Metformin-loaded nanospheres-laden photocrosslinkable gelatin hydrogel for bone tissue engineering" written by Qu L, Dubey N, Ribeiro JS, Bordini EAF, Ferreira JA, Xu J, Castilho RM, Bottino MC.

Delivery of osteogenic factors from a tissue engineering scaffold can promote craniofacial bone regeneration within a bony defect. While many studies have explored the osteogenic effects of bone morphogenetic protein-2 (BMP-2), limitations associated with its half-life and potential side effects have motivated investigation of alternative osteogenic factors for use in bone tissue engineering. A recent article by Qu et al. reports delivery of metformin from composite hydrogel constructs for bone tissue engineering. The group loaded metformin into carboxylated silica nanospheres, which they used to form composites with photocrosslinkable gelatin methacryloyl (GelMA) hydrogels. The effects of various concentrations of nanospheres on the compressive mechanical properties, swelling, and cytocompatibility were investigated in vitro. An optimal concentration of 1.5 mg/ml nanospheres was identified in terms of maximizing swelling and compressive mechanical properties of the composite, while presenting high cytocompatibility. The investigators observed sustained release of metformin from the composites over the course of 21 days in vitro. Alkaline phosphatase activity and alizarin red staining revealed significantly greater osteogenic differentiation of stem cells from human exfoliated deciduous teeth (SHEDs) cultured on composite hydrogels with and without loaded metformin, as compared with unmodified GelMA hydrogels. Overall, the study suggests the potential of the hydrogel composite as an injectable scaffold for sustained delivery of metformin as an osteogenic factor to promote craniofacial bone tissue regeneration.

Osteo Science Foundation is proud to offer a new o

Osteo Science Foundation is proud to offer a new opportunity for individuals who have not yet been accepted to an OMS Residency Program, but plan a career in OMS. The OMS Research Fellowship application cycle is currently open through January 31. Please reach out with any questions and visit osteoscience.org for more information.

"I am so honored and grateful to have been given t

"I am so honored and grateful to have been given the opportunity to attend the AAOMS Annual Meeting in Nashville. My first national experience was made possible by the Osteo Science Foundation Resident Travel Award. As a third year resident at the University of Minnesota, I was excited to experience the AAOMS meeting first hand and actually in person! It was remarkable to meet and learn from so many doctors and residents; especially female surgeons who have paved the way in Oral Surgery. Conversing with surgeons and residents alike, I received invaluable advice about my career path and future practice. The atmosphere held unsurmountable support for success and growth for everyone.

The didactic lectures were phenomenal. I particularly enjoyed the discussions of Gorlin's syndrome by Dr. Sean Edwards. Dr. Gorlin is a local legend in Minnesota and I enjoyed the discussion of the usage of sequential and multiple decompressions for recurrent OKCs.

I was extremely fortunate to reconnect with residents I had met during my externships prior to being a resident at the Osteo Science banquet. Celebrating their successes in their journey was so uplifting. I am so thrilled to rekindle old friendships, begin new ones, and return to AAOMS for my Chief year with hope to inspire those like I was inspired. Thank you Osteo Science Foundation!"
-Krista Primley

Announcing the OMS Research Fellowship! Apply now

Announcing the OMS Research Fellowship!

Apply now through January 31 for the OMS Research Fellowship. The purpose of the Fellowship is to stimulate a life-long interest in regenerative medicine research by supporting an individual who has not yet been accepted to an OMS Residency Program, but plans a career in OMS. The Fellow will work in the lab of one of the identified sites alongside an established oral & maxillofacial surgeon/researcher for a period of 12 months, and will benefit from hands-on research experience and 1:1 mentoring. Start date is July 1, 2022.

David Roe, DMD, a past Osteo Science Foundation Re

David Roe, DMD, a past Osteo Science Foundation Resident Travel Award Recipient, recently got accepted into the Clinical Observership Program! Dr. Roe visited David Urbanek, DMD, at his practice, Midwest Oral and Maxillofacial & Implant Surgery this month. To read Dr. Roe's bio or to learn more about the program visit osteoscience.org.

Myron Tucker, our Science and Education Liaison, v

Myron Tucker, our Science and Education Liaison, visited Yuanyuan Duan, DDS, PhD, at her lab at the University of Mississippi Medical Center. Dr. Kallluri gave Dr. Tucker a tour of the lab as well as a presentation and demonstration of their Osteo Science Foundation funded research project "An Article Eggshell Membrane for Guided Tissue Regeneration". We are lucky to have gotten a deeper look at their amazing work!

Yakov Yakubov, DDS, MD, is a Chief Resident in Ora

Yakov Yakubov, DDS, MD, is a Chief Resident in Oral and Maxillofacial Surgery at New York Presbyterian Hospital – Columbia University Irving Medical Center. He was born in Tashkent, Uzbekistan and grew up in Queens, New York. He completed his undergraduate studies in Neuroscience at Queens College of the City University of New York. He continued his education at Columbia University, where he earned a DDS degree in 2016 and an MD degree in 2019. His clinical interests include dentoalveolar surgery, tissue augmentation and regeneration, and implantology. Outside of the office, he enjoys spending time with his wife and daughter.

Please congratulate Dr. Yakubov for being accepted into the Clinical Observership Program! 🎉

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